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$485.22 21.78 (-4.30%)
After Hours: $485.22 +0.00 (+0.00%)
Last updated: Oct 13, 2026 22:15
52-Week Range
$485.22
$403.16 $485.22 $560.25

Fundamentals Overview

Vertex Pharmaceuticals Inc is in the middle of its 52-week range with premium valuation, trending downward today.

Valuation premium

P/E 29.5 PEG 2.5 P/B 6.23 P/S 10.31

Profitability

ROE 23.31% Net margin 35%

Risk (Beta)

0.28 — lower vol

BullzEye Analysis

Our composite tilts Hold on technicals (e.g. RSI, ADX, trend), fundamentals, sentiment, sector and index context, and risk.

Composite Signal

Sell
Buy
Hold — 55% confidence Risk: Lower Volatility — Beta 0.28. Diversify and only invest what you can afford to lose.

Pressures (Sell):

PEG 2.5 · P/S 10.31 (elevated)

Not financial advice. For education and research only; do your own research and consider a financial advisor before investing.

Key Stats

Market Cap
$128.50B
P/E (TTM)
29.46
EPS (TTM)
N/A
Dividend Yield
N/A
52-Week Range
$403.16 - $560.25
Volume vs Avg
1.15x
115% of avg (Above)
Beta
0.28

About

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex is focused on diversifying its portfolio through Casgevy (gene-editing therapy for beta thalassemia and sickle-cell disease), Journavx (non-opioid pain drug for moderate-to-severe acute...
Sector: Healthcare
Headquarters: US
Website: www.vrtx.com
Beta: 0.28 (Less volatile than market)

Financial story & AI narrative

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Valuation & Ratios

Valuation, liquidity, and profitability metrics are consolidated here (including ratios that previously appeared in the Financials story). Trailing (TTM) vs forward-looking (e.g. DCF) is noted on each line where it matters.

Metric Value
Valuation
P/E (TTM) 29.46
PEG (TTM) 2.5
P/B (TTM) 6.23
P/S (TTM) 10.31
Profitability
ROE (TTM) 23.31%
ROA (TTM) 16.88%
Revenue growth (YoY) N/A
Net margin (TTM) 35%
Gross margin (TTM) 86%
Operating margin (TTM) 37.95%
Debt to equity (TTM) 0

Latest News

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Price Target, Ratings & Grades

Analyst price targets, consensus, rating snapshot, and institutional grades for VRTX.

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Stock Grades (Institutions)

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