VRTX Add to watchlist $476.31 3.94 (-0.82%) Last updated: Jul 15, 2026 04:30
52-Week Range
$476.31
$362.50 $476.31 $533.67

Fundamentals Overview

Vertex Pharmaceuticals Incorporated is in the middle of its 52-week range with moderate valuation, trading relatively flat today.

Valuation moderate

P/E 28.1 PEG 0.05 P/B 6.25 P/S 9.86

Intrinsic value (DCF)

-15.7% downside vs price

Profitability

Net margin 35.4%

Risk (Beta)

0.29 — lower vol

Earnings & growth

EPS $16.93 Rev -7.4% Profit -13.4% vs prior qtr

BullzEye Analysis

Our composite tilts Hold on technicals (e.g. RSI, ADX, trend), fundamentals, sentiment, sector and index context, and risk.

Composite Signal

Sell
Buy
Hold — 56% confidence Risk: Lower Volatility — Beta 0.29. Diversify and only invest what you can afford to lose.

Supporting (Buy):

Analyst grade: A- · Sentiment improving (5 upgrades)

Pressures (Sell):

DCF 15.7% downside vs price

Not financial advice. For education and research only; do your own research and consider a financial advisor before investing.

Key Stats

Market Cap
$120.89B
P/E (TTM)
28.14
EPS (TTM)
$16.93
Dividend Yield
N/A
52-Week Range
$362.50 - $533.67
Volume vs Avg
N/A
Beta
0.29

About

Vertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innovative treatments, particularly for cystic fibrosis (CF). The company offers a range of approved medications for CF patients, including SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, which target specific mutations within the cystic fibrosis transmembrane conductance regulator gene. Additionally, they provide TRIKAFTA for individuals with CF aged six years and older ...
Sector: Healthcare
Headquarters: US
Employees: 6,400
IPO Date: Jul 1991
Website: www.vrtx.com
Beta: 0.29 (Less volatile than market)

Ratings & Grades at a Glance

Overall rating: A-. Recent institutional grades: majority upgrades. Current institutional positions: Buy: 9, Hold: 4, Outperform: 9, Overweight: 6, Sector Perform: 1, Underperform: 1.

Financial story & AI narrative

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Valuation & Ratios

Valuation, liquidity, and profitability metrics are consolidated here (including ratios that previously appeared in the Financials story). Trailing (TTM) vs forward-looking (e.g. DCF) is noted on each line where it matters.

DCF vs price: DCF estimate is $401.40; current price is $476.31. That’s a -15.7% gap. When the gap is large (e.g. >20%), that’s divergence; when they’re close, that’s convergence. Differences can reflect growth expectations, sector premiums, or conservative vs. optimistic assumptions. Use DCF as one input alongside technicals and sentiment.

Metric Value
Valuation
P/E (TTM) 28.14
DCF value (model) $401.40 (-15.7% vs price)
PEG (TTM) 0.05
P/B (TTM) 6.25
P/S (TTM) 9.86
P/FCF (TTM) 32.58
Liquidity & enterprise
Current Ratio (TTM) 3.02
Quick Ratio (TTM) 2.57
Cash Ratio (TTM) 1.42
Profitability
ROE (TTM) N/A
ROA (TTM) N/A
Revenue growth (YoY) N/A
Net margin (TTM) 35.4%
Gross margin (TTM) 86.28%
Operating margin (TTM) 38.97%
Debt to equity (TTM) N/A

Latest News

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Price Target, Ratings & Grades

Analyst price targets, consensus, rating snapshot, and institutional grades for VRTX.

Analyst Sentiment at a Glance

A- Sentiment Improving
Buy 9Hold 4Outperform 9Overweight 6Sector Perform 1Underperform 1
5 upgrades, 0 downgrades
Price Target Consensus
Current $476.31
Median $572.00
Consensus $547.93
Low consensus $350.00
High consensus $616.00

Stock Grades (Institutions)

Institution Action Previous Grade New Grade Date
Baird maintain Underperform Underperform 2026-07-07
RBC Capital maintain Outperform Outperform 2026-07-07
Barclays maintain Overweight Overweight 2026-05-06
Bernstein maintain Outperform Outperform 2026-05-05
Canaccord Genuity maintain Hold Hold 2026-05-05
Morgan Stanley maintain Overweight Overweight 2026-05-05
RBC Capital maintain Outperform Outperform 2026-05-05
Canaccord Genuity maintain Hold Hold 2026-04-30
Morgan Stanley maintain Overweight Overweight 2026-04-10
Maxim Group upgrade Hold Buy 2026-03-18
Truist Securities maintain Buy Buy 2026-03-11
Citigroup maintain Buy Buy 2026-03-10
Morgan Stanley maintain Overweight Overweight 2026-03-10
Oppenheimer maintain Outperform Outperform 2026-03-10
HC Wainwright & Co. maintain Buy Buy 2026-03-10
B of A Securities maintain Buy Buy 2026-03-10
Barclays maintain Overweight Overweight 2026-02-17
HC Wainwright & Co. maintain Buy Buy 2026-02-17
Canaccord Genuity maintain Hold Hold 2026-02-17
HC Wainwright& Co. maintain Buy Buy 2026-02-17
Oppenheimer upgrade Perform Outperform 2026-02-13
HC Wainwright & Co. maintain Buy Buy 2026-02-13
Stifel maintain Hold Hold 2026-02-13
RBC Capital maintain Outperform Outperform 2026-02-13
Scotiabank maintain Sector Perform Sector Perform 2026-02-13
Barclays upgrade Equal Weight Overweight 2026-01-28
UBS maintain Buy Buy 2026-01-26
Evercore ISI Group maintain Outperform Outperform 2026-01-23
RBC Capital upgrade Sector Perform Outperform 2026-01-22
Bernstein upgrade Market Perform Outperform 2026-01-12